Abstract 21

Oral leukoplakia development in patients with pre-existing oral lichen planus.

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Nita Chainani-Wu, Daniel M Purnell, Sol Silverman Jr.

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Oral leukoplakia and oral lichen planus are conditions that have the potential to transform into squamous cell carcinoma. This article describes a series of nine patients with an initial clinical-microscopic diagnosis of lichen planus. During close follow-up, these patients developed localized areas of leukoplakia at intervals ranging from one and a half to six and a half years. While both conditions may present with white and red oral mucosal changes, their management differs with leukoplakia requiring surgical intervention, therefore accurate diagnosis is imperative.

Early diagnosis and treatment of oral conditions is critical to maintain your oral and general health.